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Methylation of specific histone lysine residues serves as a publish-translational epigenetic modification that controls the expression of genes by serving as 'markers' for the recruitment of specific complexes that direct the organization of chromatin. A protein sequence alignment of the SET domains of several consultant histone lysine methyltransferases (HKMT) grouped based on their histone-lysine specificity. Lysine helps prevent the herpes virus from growing.
This could contraindicate using lysine in older adults. To our information, the influence of lysine supplementation on hepatic and peripheral glucose metabolism when given together with an OGTT has not been investigated. As well as, we integrated the appliance of secure isotope tracer methodology coupled with an OGTT that allowed us to find out the location of motion (hepatic and/or peripheral) that was influenced by lysine supplementation.
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Among them we recognized histone H3 lysine 27 acetylation (H3K27Ac) as a modification upregulated in CRC

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